If oral tolerance is acting on the same T cells that are trying to fight a cancerous tumor, this may be stopped with the knowledge provided by the nutrigenomic ImmunoDiet™. Avoiding the consumption of foods containing mutated molecular mimics, M3 peptides, is an available approach to specifically boost one’s unique anti-cancer immune response.
The immune system can recognize your normal proteins from other proteins that are considered non-self proteins and found in other living things. This function of the immune system is called self and non-self recognition and is the foundation of immunology. It is the foundation of cancer immunotherapy too.
T cells are small spherical cells that circulate the body. There are about 50,000 T cells in a drop of blood. Each T cell is able to recognize a different, short piece of protein. Another word for “short piece of protein” is “peptide”. Each peptide is made of amino acids, linked together in a string. Since there are 20 different amino acids, there are many combinations of amino acids that can be found in peptides. Luckily there are millions of T cells that can detect different combinations. T cells see peptides that are between 8 and 15 amino acids in length.
If cancer cells change the sequence of amino acids in a protein, T cells can see the difference. T cells are trained to do different things when they respond to a peptide. If the T cell was trained to kill, it will kill the cancer cell. If the T cell was trained to be neutral, it will do nothing. And if the T cells is trained to prevent kill, the cancer cell will be protected from other T cells that try to kill it.
Mutated molecular mimicry is when cancer cells mutated proteins and the new peptide is identical to a peptide in another living thing. For example, many cancer mutations change peptides to mimic beef or chicken, and hundreds of other organisms. Cancer can mimic plants and animals, also fungi and bacteria. Mutated molecular mimicry is abbreviated as M3. Each M3 peptide in a food is something unique to avoid. The more M3 peptides the high risk of suppressing the cancer specific immune response. Read about oral tolerance to learn more about this. The short answer is “do not eat your own cancer peptides”.
Oral tolerance is a crucial part of our immune function. Peptides from dietary proteins are presented to T cells after digestion. T cells that see these peptides in the lining of the digestive tract are trained to be neutral, or to shut down other T cells when it sees its peptide. Oral tolerance helps prevent food allergy. It can also block the effect of the immune response to cancer. In mice with cancer, eating M3 peptides allows its tumors to grow 25% faster. Identifying which foods contain M3 peptides is the logical first step to avoiding this outcome. The ImmunoDiet™ identifies M3 peptides in over 1400 different foods based on the testing of your tumor and normal DNA samples.
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FACT: Cancer cells can mutate to look like an ingredient in any food
This patient’s tumor cells mimic the proteins in spinach.
Only the ImmunoDiet™ can show this.
Even green smoothies may be damaging your immune system
Your ImmunoDiet™ test tells you what foods to avoid
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